The Japanese Journal of Dermatology
Online ISSN : 1346-8146
Print ISSN : 0021-499X
ISSN-L : 0021-499X
Original Articles
Isolation of Candida Albicans from the Tongues of Patients with Diabetes Mellitus (DM)
Kaoru TakayamaTakuro KatohKiyoshi Nishioka
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2003 Volume 113 Issue 7 Pages 1127-1130


We tried to demonstrate Candida albicans by the cotton swab method from the tongues of DM patients less than 60 years old ; they had no lesions. Candida albicans was isolated from 29 out of 81 patients (35.8%), as well as 4 patients (4.7%) positive by the KOH method. The mean serum HbA1c level of patients with Candida albicans was significantly higher than that of patients without it (9.4% versus 8.1%). The number of colonies of Candida albicans was correlated with the HbA1c level of the patients. The complication rate of diabetic retinopathy of patients positive for Candida albicans was 63%,significantly higher than that of patients negative for Candida albicans.

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© 2003 Japanese Dermatological Association
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