2003 Volume 113 Issue 7 Pages 1127-1130
We tried to demonstrate Candida albicans by the cotton swab method from the tongues of DM patients less than 60 years old ; they had no lesions. Candida albicans was isolated from 29 out of 81 patients (35.8%), as well as 4 patients (4.7%) positive by the KOH method. The mean serum HbA1c level of patients with Candida albicans was significantly higher than that of patients without it (9.4% versus 8.1%). The number of colonies of Candida albicans was correlated with the HbA1c level of the patients. The complication rate of diabetic retinopathy of patients positive for Candida albicans was 63%，significantly higher than that of patients negative for Candida albicans.