Abstract
We report a 47-year-old woman with erythema exudativum multiforme (EEM) who presented with ulcerative colitis (UC). She developed multiple erythema with vesicular formations, mainly on the extremities and accompanied by slight deterioration of the conjunctiva and lip, at the same time that the UC symptoms appeared. The biopsy revealed a keratinocyte necrosis, interface dermatitis in the epidermis, and perivascular infiltration of mononuclear cells. leading to the diagnosis of EEM. We were able to rule out drug-induced eruptions and infectious eruptions. UC is rarely associated with EEM. There has been no report of UC association with EEM in Japan. It is necessary to take into consideration the complication of UC occuring with EEM.
