Lymph Node Metastasis and Sentinel Lymph Node Biopsy in the Extramamary Paget’s Disease

Abstract

A statistical analysis was performed on 23 examples of lymph node metastasis among 95 patients with extramamary Pagetʼs disease in the Division of Dermatology, National Cancer Center Hospital, from 1962 until 2005. Although lymph node metasyasis had distinguished by the difference between one side or two sides in “the TNM classification of Paget disease (proposal)” which Ohara advocated in 1992, the five-year probability of survival with more than two lymph node metastasis was only 13.5%, but that with one lymph node metastasis was 100%. So it is necessary to improve the standard of lymph node dissection to above two lymph node metastasis, We examined whether we could judge exactly one lymph node metastasis or above two lymph node metastasis with a sentinel lymph node biopsy.