The Japanese Journal of Dermatology
Online ISSN : 1346-8146
Print ISSN : 0021-499X
ISSN-L : 0021-499X
Original Articles
Eccrine Angiomatous Hamartoma: Report of Three Cases and a Literature Review of Japanese Cases
Eiichi MakinoHiroaki HayashiMakoto InaokiWataru Fujimoto
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2006 Volume 116 Issue 2 Pages 185-192

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Abstract
We reported three cases of eccrine angiomatous hamartoma (EAH), a benign proliferation of eccrine structures and angiomatous channels in the dermis, and identified 46 Japanese cases in a literature review. In Case 1, a 74-year-old man presented with a sacral nodule. In Case 2, a 70-year-old man presented with a reddish plaque on the right heel. In Case 3, a 22-year-old man presented with a violaceous plaque on the right lower leg. Analysis of all 49 cases revealed a male : female ratio of 17 : 32. Age at presentation ranged from birth to 74 years (mean : 20.3 years), and 36 of the 49 lesions (73.5%) developed before 10 years of age. Most lesions (91.8%) were located on an extremity, and 73.5% were solitary. Lesional pain and sweating occurred in about 60% of patients. Cases were separated into two groups : patients younger than 10 years of age and patients 10 years of age and older. The latter group was more likely to have lesions of the sole and less likely to have lesions of the finger. Hypertrichosis was rarely seen in the older group.
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© 2006 Japanese Dermatological Association
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