The Japanese Journal of Dermatology
Online ISSN : 1346-8146
Print ISSN : 0021-499X
ISSN-L : 0021-499X
Original Articles
The Effects of Rush Immunotherapy on Hymenoptera Allergy
Junko MurayamaHiroko TaniguchiMasatoshi GodaEri NakamuraYuko HiraiHiroko OnoNaoko MotohashiChohei TakinoNoriko Ohtaki
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2007 Volume 117 Issue 2 Pages 163-168


Six patients who had each experienced a systemic reaction to a hymenoptera sting received rush immunotherapy. Medical indications for venom immunotherapy are patients who have had a history of systemic reactions such as hypotension, unconsciousness, and dyspnea. The venom extracts were imported from Hollister-Stier, USA. The patients had received subcutaneous injections 2 to 4 times a day for 2 weeks with hospitalization, and then they had received maintenance injections once a month as outpatients. All the patients had local side effects, and one developed generalized urticaria during immunotherapy. Two patients suffered re-stings during the maintenance therapy. One had no reaction, and another one exhibited a full anaphylactic reaction again, but he recovered with emergency treatment. We recommend that our patients carry an EpiPen during maintenance therapy.

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© 2007 Japanese Dermatological Association
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