Abstract
We reported a case of 83-year-old woman with a burnt umber nodule on the abdomen, which previously had been histologically diagnosed as a nevocellular nevus on biopsy at another hospital. However, as the nodule gradually enlarged, we have established a diagnosis of superficial spreading melanoma uslng dermoscopy findings demonstrating an atypical pigment network, irregular streaks, irregular globules, and a blue-whitish veil.The lesion consisted of atypical tumor cells and nevoid cells with mild atypism and the latter showed weak reactivity with HMB-45 staining. However, they both demonstrated strong reactivity against PCNA staining and a continuity with pagetoid tumor cells. We concluded that these cells were a series of malignant cells. These biological and morphological variations must be an evidence of malignancy.
