2008 Volume 118 Issue 12 Pages 2421-2428
We analyzed 1,657 samples from bacteria-associated cutaneous disorders seen during the summer periods from June to September for 7 years from 1998 to 2004 in our dermatological out-patient office. Among the 1,960 bacterial isolates, 1,372 Staphylococcus (S.) aureus [1,064 methicillin-sensitive S. aureus (MSSA) and 308 methicillin-resistant S. aureus (MRSA)], 165 coagulase-negative staphylococci, 128 hemolytic streptococci, and 295 other bacterial species were identified. Thus, 22.4% of the isolated S. aureus were MRSA. Nasal cultures from patients with MRSA-isolated skin lesions in 2004 indicated 54.1% nonsymptomatic MRSA residence in the nasal cavities of these patients. Bacterial susceptibility to antibiotics was analyzed with NCCLS (CLSI) criteria for Kirby-Bauer disc method. Almost all the MSSA isolates were susceptible to cephem antibiotics. However, the MSSA susceptibility to gentamicin decreased from 43.8% to 30.9%. Susceptibility of MRSA in 1998 and 2004 were 100% and 96.3% to minocycline, 78.6% and 77.7% to fosfomysin, and 71.4% and 70.4% to tetracycline, respectively. All the cases of MRSA-isolated skin lesions in 1998 and 2004 were followed completely to confirm the effect of chemoterapy. They were all cured, mostly with therapy combining cefdinir and fosfomysin or with minocycline alone.
