Abstract
To examine the clinical characteristics of drug-induced psoriasis in Japan, we retrospectively analyzed 34 cases of drug-induced psoriasis which were treated in our hospital from January 2000 to May 2012. Nineteen males and 15 females were included. Major causative drugs were antihypertensive drugs (63.6%) including a calcium antagonist, followed by nonsteroidal anti-inflammatory drugs (NSAIDs), litium, and anti-TNFα drugs. Clinical manifestations varied, but plaque type of psoriasis was observed most frequently. Pathological manifestation included findings of both psoriasis and lichenoid reaction. It is important that dermatologists take drug-induced psoriasis into consideration when patients being treated with medication develop psoriasis.
