A Questionnaire-based Study to Assess Adverse Reactions in Medical Professionals Who Were Mass-vaccinated against COVID-19 in Our Hospital

Abstract

We performed a questionnaire-based study to assess local and systemic adverse reactions in 677 medical professionals who were vaccinated with the Pfizer-BioNTech vaccine against COVID-19 in our hospital. The results show that the frequency of systemic adverse reactions was significantly higher after the second dose than the first; the frequency of systemic adverse reactions after the second dose was significantly higher in women than in men; and the frequency of systemic adverse reactions after the second dose was significantly higher in individuals with a history of allergies than in those without. In addition, the frequency of all adverse reactions was significantly lower in patients over 60 years old. Furthermore, the frequency of all adverse reactions peaked the day after vaccination in more than half of the cases. These results are useful for managing expectations following general vaccination against COVID-19.