2025 Volume 135 Issue 1 Pages 73-83
We retrospectively analyzed 11 cases of eosinophilic granulomatosis with polyangiitis that we experienced in our department during the recent 12 years. Patients included 7 males and 4 females. All except 2 cases had asthma and various organ involvement; renal (n=4), cardiac (n=2), peripheral nerve (n=9), pulmonary (n=6), and gastrointestinal (n=3) manifestations were observed. Laboratory findings included increased levels of IgE (n=9), peripheral blood hypereosinophilia (n=10), and positive antineutrophil cytoplasmic antibody (ANCA) (n=4). Fourteen biopsy specimens revealed prominent eosinophil infiltration in the dermis in every case. In addition, we observed various cutaneous vasculitis variants including leukocytoclastic vasculitis (n=4), eosinophilic vasculitis (n=3), and granulomatous arteritis (n=3). This study examined various types of cutaneous vasculitis and their associations with ANCA and organ involvement.
