2006 Volume 15 Issue 2 Pages 43-47
We report the case of a 14-years-old neutered shiba dog suffering from anorexia and vomiting that was treated successfully by combination chemotherapy after diagnosis of plasma cell leukemia, and has been in complete remission. Hematological tests revealed pancytopenia with an increased number of plasma cells, monoclonal gammopathy, and hypercalcemia. Bone marrow aspiration showed that plasma cells had increased to over 90%. On the basis of serum immunoelectrophoresis, serum M component was classified as immunoglobulin A(Ig A). Radiography identified no osteolytic foci. These findings confirmed a diagnosis of plasma cell leukemia. Combination chemotherapy using vincristine, prednisolone, and melphalan was perfomed on the dog. Until now, namely up to day 240, the dog has been in good health, and in complete remission.
