Abstract
In preliminary research to establish an effective method for prevention of blood sucking by mosquitoes on animals, experiments were carrid out with 24 hairless rats (HWY/Slc, males, 4 weeks old), which were assigned to 4 groups of 6 animals each. One group was an unmedicated control and the other 3 groups were treated with a permethrin pour-on formulation at a dose of 100 mg active ingredient per kg body weight, a fipronil spot-on formulation at a dose of 7 mg/kg and an imidacloprid spot-on formulation at a dose of 10 mg/kg, respectively. The rats were individually caged and left for 30 minutes in an environment where a large number of mosquitoes, chiefly Culex pipiens pallens, were flying around. The number of mosquitoes sucking the blood of rats was significantly (p<0.05) lower in the group treated with permethrin than in the control group. In the groups treated with fipronil or imidacloprid, on the other hand, no preventive efficacy was observed. Further, a dog and a domestic cat were treated with the same formulation of permethrin at the same dosage and kept on a leash in the same environment, which demonstrated the preventive efficacy against mosquitoes.
