Liver Biopsy in Eight Young Cats with Persistently High Serum Liver Enzyme Activity

Abstract

Liver biopsy was carried out in eight, healthy-looking, young cats with elevated serum liver enzyme activity. Increased enzyme activity had been noted before spaying or castration, and at medical checkups, but no medical treatment had been effective. Histopathological tests showed suppurative cholangiohepatitis in four cats, lymphocytic cholangiohepatitis in one cat, and hydropic degeneration in the other three cats. The results suggest that there is a possibility of these liver diseases if serum liver enzyme activity remains persistently high in spite of medical treatment in young cats.