Abstract
Extended-spectrum β-lactamase(ESBL)-producing Klebsiella pneumoniae, a bacterium newly resistant to many kinds of β-lactams, has caused serious problems in humans, but no canine data on ESBL-producing K. pneumoniae are available in Japan. A ten-year-old, castrated Shih Tzu was suffering from intractable cystitis infected with ESBL-producing K. pneumoniae after removal of urinary bladder stones. Administration of doxycycline, amoxicillin-clavulanic acid, trimethoprim- sulfamethoxazole, or amikacin was not very effective, but oral administration of faropenem, a penem antibiotic, was effective. The dog made a complete recovery. We need to take precautions against the future prevalence of ESBL-producing bacteria in hospitals.