Diminished Thymoma by Treatment with Cyclosporine in a Rabbit

Abstract

An 8-year-old rabbit was brought to us with the complaints of chronic exfoliative dermatitis, systemic allopeecia, bilateral exphthoalmos, and dyspnea. In several examinations, a thymoma was found in the anterior mediastinum. The dog’s cutaneous symptoms were considered to be paraneoplastic sebaceous adenitis. As the pet owner requested us to ease only the symptoms of sebaceous adenitis, oral treatment with cyclosporine was started on the basis of reported successful remedy of sebaceous adenitis in dogs. The size of the thymoma was decreased, and the bilateral exophtalmos and dyspnea were reduced. This case showed the possibility that cyclosporine can decrease the size of a thymoma in rabbits.