2023 Volume 32 Issue 1 Pages 11-
We retrospectively investigated the association between vaccination frequency and chronic kidney disease (CKD) and its prognosis in cats. Cats included in the study received eight different vaccines, which contained cells derived from the cats’ kidneys. Age at onset of CKD was 15.4 ± 3.3 years in the unvaccinated group, 14.2 ± 3.1 years in the low-frequency, and 13.6 ± 2.7 years in the high-frequency vaccination group. We observed no significant intergroup difference in age at onset of CKD. The incidence of CKD was 22.6% in the unvaccinated group, 32.5% in the low-frequency vaccination group, and 49.0% in the high-frequency vaccination group, and 36.7%. The odds ratio of the high-frequency vaccination group compared to the low-frequency vaccination group was 1.99(95% CI:1.08-3.68,p<0.05). These results highlight that vaccination may serve as a risk factor for feline CKD.
