Developmental Origins of Health and Disease Research
Online ISSN : 2187-2597
Print ISSN : 2187-2562
Significant role of intestinal microbiota for DOHaD
Yuichiro YAMASHIRO
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2023 Volume 11 Issue 2 Pages 135-142

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Abstract

The prenatal (in utero) environment is now recognized as a key driver of non-communicable diseases (NCDs) risk later in life, namely called as developmental origins of health and disease (DOHaD). The current studies are increasingly links between diverse stressors during pregnancy and the risk to offspring of a milieu of NCDs, including cardiovascular disease, metabolic disorders. On the other hand, our intestinal microbiota are extremely important for the preservation of human health and the changes in these bacterial communities (dysbiosis) are linked to disease states such as NCDs. This review paper describes methods of the microbiota manipulations in pregnancy, infant and children with dysbiosis, using probiotics and nutrition.

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© 2023 Japan Society for Developmental Origins of Health and Disease
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