DEEP OCEAN WATER RESEARCH
Online ISSN : 1884-958X
Print ISSN : 1345-8477
ISSN-L : 1345-8477
Suppressive effect of deep seawater on the calcification of normal human fibroblasts induced by UVA irradiation
Katsuhisa YAMADAYuji SHIBATAMichiyasu NOMURAChiaki IMADA
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JOURNAL OPEN ACCESS

2017 Volume 18 Issue 1 Pages 1-7

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Abstract
We have previously reported in this journal that the increase in Ca/Mg ratio and the aging of cells promote calcication of cultured normal human fibroblasts (NB1 cells). In this report, it is suggested that A-wave ultraviolet rays (UVA) induces calcification of NB1 cells even if the Ca/Mg ratio in culture medium is well balanced as 2. Furthermore, we have discovered that deep seawater (DSW) suppresses the calcication induced by UVA irradiation. In addition, suppressive effect of DSW was much higher than that of SSW. From these results, it was suggested that the suppressive eect of DSW on calcification in NB1 cells was caused by specific components included in DSW.
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© 2017 DEEP OCEAN WATER RESEARCH
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