Abstract
We have previously reported in this journal that the increase in Ca/Mg ratio and the aging of cells promote calci cation of cultured normal human fibroblasts (NB1 cells). In this report, it is suggested that A-wave ultraviolet rays (UVA) induces calcification of NB1 cells even if the Ca/Mg ratio in culture medium is well balanced as 2. Furthermore, we have discovered that deep seawater (DSW) suppresses the calci cation induced by UVA irradiation. In addition, suppressive effect of DSW was much higher than that of SSW. From these results, it was suggested that the suppressive e ect of
DSW on calcification in NB1 cells was caused by specific components included in DSW.
