A Case of Paroxysmal Kinesigenic Dyskinesia with Complex Partial Seizure Probably Associated with Amygdala Enlargement

Abstract

Paroxysmal kinesigenic dyskinesia (PKD) is a rare disease characterized by involuntary movements triggered by a sudden initiation of voluntary movement. No EEG abnormalities are observed both during and between PKD attacks. Clinically, the involuntary movements are readily controlled by sodium channel-related antiepileptic drugs such as carbamazepine [1] and phenytoin [2]. Two hypotheses have been proposed for the pathophysiology of PKD; kinesthetic reflex epilepsy [3] and basal ganglia functional abnormality [4], but no consensus has been reached.
We report a patient with amygdala enlargement who manifested complex partial seizure (CPS) following PKD attack.