2025 Volume 83 Issue 2 Pages 71-77
Objective: To evaluate the effects of the timing and the amount of pre-meal ingestion of salt-grilled salmon (SGS) on postprandial plasma glucose levels in healthy young adults.
Methods: In the morning after fasting overnight, 11 young healthy subjects in their twenties: ingested 150 g of cooked rice (CE) followed by 120 g of SGS, 30 min later (Experiment A); 120 g of SGS followed by 150 g of CE, 30 min later (Experiment B); 120 g of SGS followed by 150 g of CE, 5 min later (Experiment C), and 40 g of SGS followed by 150 g of CE, 30 min later (Experiment D), on different days. Plasma glucose levels were measured before and at 15, 30, 60, 90, and 120 min after CE ingestion, and then glucose incremental area under the curve (IAUC) was calculated.
Results: Plasma glucose levels 30 min after CE ingestion were significantly lower in experiment B than in experiment A (p < 0.05), and those 60 min after CE ingestion of were significantly lower in experiments B and C (p < 0.05). The IAUC was significantly lower in experiments B and C than in experiment A (p < 0.05), but was not statistically significant in experiment D.
Conclusion: Even when the timing of pre-meal ingestion of SGS was shortened from 30 min to 5 min before meals, the increase in plasma glucose levels after meals was suppressed. We also found that a certain amount of protein is necessary to suppress the increase in postprandial plasma glucose levels.
