Abstract
Deranged lipid metabolism in patients with chronic renal failure is characterized by hypertriglyceridemia and low plasma HDL-cholesterol concentration. These abnormalities may be one of the risk factors for developing atherosclerosis, and may shorten the life span of dialyzed patients. In the present study, we tried to discuss the effects of polyunsaturated fatty acid-rich diet on the lipid metabolism of patients with chronic renal failure. Serum triglycerides significantly decreased by ingestion of polyunsaturated fatty acid-rich diet. Atherogenic index also elevated and LCAT decreased through the polyunsaturated fatty acid-rich diet.
In conclusion the ingestion of a polyunsaturated fatty acid-rich diet can improve deranged triglyceride metabolism and atherogenic index in patients with chronic renal failure and may be effectivee for prevention of atherosclerotic vascular sequellar. However, most suitable P/S ratio in the diet has yet to be determined.
