2008 Volume 66 Issue 6 Pages 287-294
The effects of dietary biscuits containing medium-chain triacylglycerols (MCTs) on the post-prandial blood lipid and glucose levels in healthy humans were investigated. Seven volunteers ingested biscuits containing 33g of MCT or 33g of long-chain triacylglycerols (LCTs) and functional saccharide sweeteners. The two test biscuits were given with a seven-day interval between. Blood samples were immediately collected, and 2 and 4 hours after ingestion.
The serum triacylglycerol (TG) level significantly increased after ingesting the LCT biscuit, but not after the MCT biscuit. The serum remnant-like particle cholesterol (RemL-C) level also significantly increased after ingesting the LCT biscuit, but not after the MCT biscuit. RLP-C showed the same tendency. These data suggest that the MCT biscuit may have suppressed the post-prandial elevation of RemL-C that is thought to develop or progress with arteriosclerosis. Moreover, the blood glucose level was significantly lower after ingesting the MCT biscuit than after the LCT biscuit. However, ketones significantly increased after ingesting the MCT biscuit.
The overall results suggest that the MCT biscuit may endow a lower risk of post-prandial lipemia and hyperglycemia than the LCT biscuit, although more extensive trials are needed to confirm these preliminary findings.
