2019 Volume 1 Issue 4 Pages 236-241
Purpose: Recent investigations have demonstrated that preoperative serum prealbumin (PreAlb) concentration is a useful predictor of postoperative complications after Gastrectomy. However, the association of serum PreAlb concentration with lung cancer surgery remains unclear. The aim of this study was to examine the association between the onset of postoperative respiratory complications and preoperative serum PreAlb level in patients who underwent lung cancer surgery.
Subjects and Methods: The medical records of primary lung cancer patients who underwent thoracoscopic lobectomy from January 2014 to December 2016 were retrospectively reviewed, and the clinicopathological features of these patients were compared between patients with and without postoperative respiratory complications. Furthermore, risk factors for postoperative respiratory complications were extracted using logistic regression analysis. Results: Among 449 patients, 29 patients (6.5%) developed postoperative respiratory complications. Both PreAlb and body mass index (BMI) values were significantly lower in patients with complications than in those without; the proportions of men, heavy smokers, and the prevalence of diabetes were significantly higher among patients with complications than those without. Multivariable analysis showed that PreAlb, BMI, and smoking index were significantly associated with the development of postoperative respiratory complications. Conclusion: The findings of our study suggested that low preoperative PreAlb level, in addition to low BMI and smoking index, would be a simple and useful factor for predicting the development of postoperative respiratory complications.
