Abstract
The rabbts were divided into 4 groups: (1) the control (2) two hours,(3) four or five hours, after the injection of alloxan, especially in an attack of a hypoglycemic shock (4) diabetic phase after 48 hours. Rabbts were gived alloxan (generally 200 mg/kg) intravenously following 48 hours fast, and liver glycogen, muscle giycogen and heart glycogen were determined in each phase.
1) Liver glycogen decreased in the initial hyperglycemic phase, came to its contain of normal rabbit in the hyoglycemic phase. Liver in the diabetic phase contained markedly less glycogen than normal rabbit liver.
2) Muscle in the initial hyperglycemic and the diabetic phase contained less glycogen than normal rabbit muscle, especially markedly in the hypoglycemic phase.
3) The fluctuation of heartglycogen was very interesting. Heart in the hypoglycemic phase contained more glycogen than normal rabbit heart, especially markedly in the diabetic phase.