Studies on Glucose-6-Phosphatase in Liver and Kidney

II. Relationship between Thyroid Hormones and Glucose-6-Phosphatase in Rat Liver and Kidney

Abstract

Variation of glucose-6-phosphatase (G6Pase) activity in rat liver and kidney under thyroidal dysfunctioning was investigated on the groups of experimental animals treated as follows :
a) Potassium iodide administration; 10γ per day for a week b) 3, 3', 5'-Triiodothyronine administration; 5γ per day for a week c) L-Thyroxine administration; 30γ per day for a week d) Mercazole administration; 10 mg per day for a week e) Thyroidectomy; more than 4/5 of the thyroid gland removed f) Thyroxine administration (30γ per day for a week) after thyroidectomy