Comparison of the Blood Characteristics among 4 Strains of Inbred Mice

Abstract

Erythrocyte count, leukocyte count, hemoglobin content, serum protein percentage, leukocyte diagnosis were determined in the blood of adult male of 4 different inbred strains mice, dd, rr, ss, and C57BL.
After the means and standard errors for each determination were given for each strain. Statistical significance was tested among the 4 strains.
There were significant genetic differences among the strains in factors affecting erythrocyte number, leukocyte number and hemoglobin content. On the other hand, protein percentage failed to show appreciable variability among the strains. The leukocyte diagnosis, concerning with neutrophile, varied significantly between rr and C57BL.
Erythrocyte number was 1055±64 in dd, 1090±66 in rr, 994±80 in ss and 1117±78 in C57BL (ten thousand) . Leukocyte number was 8, 560±1, 628 in dd, 8, 013±1, 655 in rr, 6, 725±1, 696 in ss and 5, 046±2, 242 in C57BL.
Hemoglobin content was 15.29±1.01 in dd, 16.74±0.68 in rr, 15.53±1.20 in ss and 15.51±1.15 in C57BL (g/dl) .