Abstract
Natural hemagglutinins against chick erythrocytes in mouse sera were studied with several inbred strains established in Japan. When the chick erythrocytes of Nagoya breed (line B) were used for hemagglutination test, the percentage of animals possessing the agglutinins was as follows; CS: 18.5, NC: 44.2, KK: 45.9, DDK: 50.7, CF#1: 42.1, C57BL/6: 58.3.
It was found that the agglutinating capacity of the mouse sera differs markedly according to cells used. The mouse sera which failed to agglutinate the cells from the Nagoya breed, showed strong positive reaction with the cells from the Jito groups of chicken.
Reciprocal absorption tests revealed that there are at least two qualitatively different agglutinins in mouse sera. It may be suggested that the hemagglutination caused by mouse sera could be a useful tool for the classification of chick erythrocyte groups.
