Canine Parvovirus Infection in a Group of Beagles

Abstract

An outbreak of canine parvovirus infection in a group of 26 beagles was described. The disease characterized by acute intestinal involvement was highly contagious but fatality was low (1/26) . Transient leukopenie was recorded in some animals. All the convalescent sera were positive in agar gel diffusion test using feline panleukopenia virus antigen. Histopathological examination on fetal dog revealed regressive change associated with formation of amphophilic intranuclear inclusion bodies in the enterocytes of the Lieberkuhn's crypt and regressive change in the lymphoid tissues. Pathologic picture exhibited strikingly resemblance with that of feline panleukopenia.