Experimental Animals
Online ISSN : 1881-7122
Print ISSN : 0007-5124
Use of CO2 Euthanasia Cabinet for Experimental Animals
Tsutomu KUROSAWAHiroshi TAMURAJun-ichi SHIKATAKazuyoshi MAEJIMAYoshio TAKAGAKIMasao NAKAGAWAKiyoshi SUZUKI
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JOURNAL FREE ACCESS

1981 Volume 30 Issue 3 Pages 317-321

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Abstract
The process of CO2 euthanasia on mouse, rat, guinea pig and rabbit was observed using a CO2 euthanasia cabinet. The cabinet was filled with CO2 gas and the caged animal was placed into the cabinet. These animals quietly collapsed and their respiratory movement ceased within 25-225 seconds. A-V block was the first arrhythmia recognized on ECG in all cases. The arrhythmia recorded on ECG included complete A-V block, A-V dissociation, ventricular escape rhythm, atrial fibrillation, ventricular flutter and ventricular fibrillation. It could be concluded that euthanasia was satisfactorily performed on these species by means of the CO2 euthanasia cabinet.
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© Japanese Association for Laboratory Animal Science
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