1984 Volume 33 Issue 1 Pages 115-120
Eleven pathogens includingP. aeruginosa, Salmonellaspp., E. coliO115a, c: K (B), P. pneumotro pica, B. bronchiseptica, C. kutscheri, Tyzzer's organism, M. pulmonis, Sendai virus, MHV andSyphaciaspp. were surveyed in 217 mouse and rat breeding colonies during 1972-1981. In conventional animals, P. Pneumotro picaand / orSyphaciaspp. were detected in nearly 90 % of 89 mouse and 64 rat colonies. Sendai virus, M. pulmonis, P. aeruginosaand MHV were positive in 51.7 to 23.6 %of the colonies, and Tyzzer's organism, B. bronchisepticaand probably SDA virus were also detected in more than 10 % of the rat colonies.Salmonellaspp., E. coliO115a, c : K (B) andC. kutscheriwere found in a few colonies. In SPF animals, P. aeruginosawas isolated from about one third of 33 mouse and 31 rat colonies, andP. pneumotropicawas also positive in 3 rat colonies, Infection rates ofP. pneumotropica, M. pulmonis, Sendai virus andSyphaciaspp. were usually higher than 40 % of animals sampled from colonies contaminated with them. Accidental contaminations of SPF colonies were usually caused byP. pneumotro pica and Syphaciaspp.