Serologic and Virologic Surveys on Feline Herpesvirus and Feline Calicivirus Infections in Cats for Experimental Use

Abstract

Serologic survey and virus isolation of feline herpesvirus (FHV) and feline calicivirus (FCV) were performed on cats used for research at the Laboratory Animal Research Centre, The University of Tsukuba, over the period from 1978 to 1981. Of the 507 mature and immature cats, 4 months old or older, 102 (20.1 %) had HI antibody against FHV and 412 (81.3%) SN antibody against FCV. Some 23 (16.2 %) and 76 (53.5 %) kittens among 142 younger than 4 months had antibodies against FHV and FCV, respectively. Both the antibodies in kittens were considered to be maternally derived. The FCV antibody rate was especially high in cats weighing 2.5 kg (males) and 2.0 kg (females) or more, which were regarded as 8 to 10 months of age. An attempt was made to isolate the viruses from the oropharynx and conjunctiva of clinically healthy mature or immature cats and kittens. As the result, either one or both of the viruses were isolated from 31 of 75 mature and immature cats, and isolation rates of FHV and FCV were 6.7 % and 36.0 %, respectively. On the other hand, no virus was detectable in 16 kittens.