Pathology of Aspiration Pneumonia in Mice

Abstract

A aspiration pneumonia caused in 3 female mice by food inhalation was examined histopathologically. Dark-red areas were observed macroscopically on the uncut lungs. The change was more severe in the superior and post-caval lobes of the right lung and the anterior part of the left lung. Microscopic examination revealed various-sized foreign bodies (inhaled food particles) accompanied by inflammatory cells and microorganisms in the tracheal lumen and the bronchiolar and alveolar spaces.