Experimental Animals
Online ISSN : 1881-7122
Print ISSN : 0007-5124
Effects of Repeated Chair Restraint on Physiological Values in the Rhesus Monkey (Macaca mulatta)
Tetsuo TATSUMIMasao KOTOHiromichi KOMATSUJiro ADACHI
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JOURNAL FREE ACCESS

1990 Volume 39 Issue 3 Pages 361-369

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Abstract
The purpose of this study was to examine the effects of repeated chair restraint on some physiological values in the rhesus monkey. Although heart rate and blood pressure increased significantly at the onset of chair restraint, these increased values gradually decreased with repetition of restraint as well as with the lapse of time after restraining. Finally, no elevation of these levels was detected after repetitions lasting eight hours per day for five days. Plasma cortisol, CK and GOT values also showed similar trends. These elevated physiological values at the onset of chair restraint seemed to be due to high sympathetic tone and muscular activity used to try to avoid the restraint. It is concluded that repeated chair restraint has an accommodative component in monkeys resulting in the return of some elevated physiological values to the normal level.
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© Japanese Association for Laboratory Animal Science
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