Experimental Animals
Online ISSN : 1881-7122
Print ISSN : 0007-5124
Ragged—A New Rexoid Mutant Rat with Large Sebaceous Gland—
Junko NOGUCHIChiyo AJISAWAHiroshi IKADAITomonori IMAMICHI
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JOURNAL FREE ACCESS

1990 Volume 39 Issue 3 Pages 383-388

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Abstract
A new hair defected mutant rat was established. This mutant was covered with ragged hair since about 10 days of age, then transiently lost most of hair in the back at approximately 5 weeks of age and was re - covered with ragged hair thereafter. Thickened eyerids occurred since about 3 weeks of age. Histological examination revealed enlarged sebaceous glands with greater number of sebaceous cells in the back skin. The oil stained skin samples showed normal sebaceous transformation and pilosebaceous canal. Genetical analysis showed that the ragged hair character was a single recessive trait and indicated that this single recessive gene was not linked with the coat color genes, non-agouti (a), albino (c) and hooded (h) . From the present data and previous reports, we recomended this single recessive gene is a new rexoid mutation thereby we termed this gene “Ragged (rg) ”.
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© Japanese Association for Laboratory Animal Science
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