Changes in Rhythmicity of Ambulatory and Drinking Activities in Immature Female Rats

Abstract

Adult female rats showed increase in ambulatory activity and marked decrease in drinking behavior at early dark period (18: 00-24: 00) of proestrus stage before ovulation. In this study, we observed the changes in patterns of ambulatory and drinking activities of immature rats associated with estrous cycle during growing period. Immature female rats of the Wistar-Imamichi strain were used, and both behavioral activities were measured continuously, using Gundai type Ambulodrinkometer. From these observations, it was found that the typical patterns of ambulatory and drinking activities which were observed in adult female rats appeared at the sixth (51-60 days old) and the third (39-49 days old) estrous cycle, respectively.