Abstract
In this study, the ethanol injection method was utilized to encapsulate thioglycolic acid (TGA) in liposomes, and 4 lipid formulations were designed to assess the effects of liposome-encapsulated TGA on hair perming. The results showed that the diameter of liposomes without cholesterols was between 112.5 nm and 124 nm, and the diameter expanded to 288 nm to 325 nm after supplementing the liposome particles with cholesterols. The S-shaped waving of hair treated with a pH 9.0 liposome hair perm solution after 4 hair washes was around 19.06 % to 24.73 %, which was higher than the 17.27 % of the control group. Analyses of the cysteine content in hair treated with the first perm solution revealed that the cysteine content in the control group was about 4.40 %, whereas that of the experimental group was 4.51 % to 5.31 %. These results demonstrated that liposomes facilitate the penetration of perm solutions into the hair cortex to cleave the disulfide bonds, thus enhancing the reduction capacity of the first perm solution.
