Analysis of Diarrhetic Shellfish Toxins in Mussels from the Adriatic Coast of Italy

Jiaping Zhao; Giampaolo Cenci; Eraldo Di Antonio; Takeshi Yasumoto

doi:10.2331/fishsci.60.687

Jiaping Zhao, Giampaolo Cenci, Eraldo Di Antonio, Takeshi Yasumoto

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Keywords: DSP, Italy, Adriatic Sea, HPLC, okadaic acid, new toxins, mussel, diarrhetic shellfish toxin

JOURNAL FREE ACCESS

1994 Volume 60 Issue 6 Pages 687-689

DOI https://doi.org/10.2331/fishsci.60.687

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Abstract

Diarrhetic shellfish toxins in mussels collected from the Adriatic coast of Italy were analyzed by both mouse bioassay and fluorometric high performance liquid chromatography (HPLC). Of eleven specimens tested, one each from Trieste, Rimini, and Ancona proved to be toxic in the mouse bioassay. In each case, okadaic acid was confirmed as the major toxin by HPLC analysis, but in addition to okadaic acid, unprecedented toxins having cytotoxic activity were found to be present in a Rimini sample.

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