Abstract
Chromosome manipulation has been developed so as to develop a systematic technology applicable for genetic improvement of aquaculture species by combining with related techniques such as hormonal sex-control and conventional hybridization. This paper reviews current status of the monosex, sterile, allopolyploid and isogenic populations practically used in the aquaculture of salmonids. Chromosome manipulation would be promising, if it integrated with modem molecular techniques to promote genomics, transgenics and other biotechnology and then to develop more advanced system useful in future aquaculture.