Abstract
Inhibitors obtained from macroalgae against α-glucosidase and urease were investigated. Alpha-glucosidase inhibitors obtained from the red algae of Rhodomelaceae family were identified as bromophenols. Symmetric bisbenzyl ethers strongly inhibited Saccharomyces cerevisiae α-glucosidase, compared with the others. Inhibitors against α-glucosidase and urease were obtained from the brown algae Pelvetia babingtonii (Fucaceae) and Alaria crassifolia (Alariaceae). The inhibitors were identified as phlorotannins. P. babingtonii phlorotannin decreased blood glucose levels in sucrose-loaded rats.
