Pharmacological studies on decomposition and resorption of aconitine group

II. On the resorption of aconitine, mesaconitine and jesaconitine from tissues

Abstract

The hydrochloride salts of aconitine, mesaconitine, jesaconitine (all Suginome's) and aconitine (Merck) were applied to intact skin, external auditory canal, conjunctival sac, nasal or oral cavity, esophagus, stomach, small intestine, glans penis or vagina of animals in the form of watery solution, alcoholic solution, ointment or powder and it has been found that these drugs are, even in minute doses, rapidly absorbed from epithelial tissues, skin and mucous membrane of test animals.