Abstract
Tested compounds were camphor, trans π-, 10-, p-, o-oxocamphor, trans π-oxycamphor, isoketopinic acid and Coramine. Among them, merely 1x 10-4m trans n-oxocamphor transiently increased the cardiac efficiency by 20% (The O2-uptake of heart decreased by 20%, while the cardiac output and aortic pressure did not show any remarkable change.). The decreased O2-uptake and augmented aerobic lactic acid formation of rat's brain and cardiac muscle slices by 5x10-3m of it was observed, and it was proved that this phenomenon was the influence on Pasteur effect through the inhibitory effect on the dehydrogenase systems. 10-Oxocamphor also had similar effects on tissue respiration.
