Abstract
It has been found by Hongo that Ringer's solution, kept with rabbit plasma for 18 hours at 38°C, decreased the blood pressure in cats. The present study aimed to follow the mode of action of this substance, being employed this plasma as a solid component of the tissue culture medium in the Carrel's bottle. Result : The hypotensive effect for cat was not affected by the preliminary intravenous injection of atropine and benadryl, while it was antagonized by adrenaline. Such a hypotensive action was not observed in rabbit and it was also proved that this substance had no effect on the uterus of albino rat.
