Folia Pharmacologica Japonica
Online ISSN : 1347-8397
Print ISSN : 0015-5691
ISSN-L : 0015-5691
Studies on d-trans-7-aldehyde-π-apocamphor (Vitacamphor)
Report II. Its mode of action and of other aldehydes on the dehydrogenase system and their fate in animal tissues
Yoshiko MORITA
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1955 Volume 51 Issue 2 Pages 94-106,en12

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Abstract
1) Benzaldehyde, anisaldehyde, and other aldehydes, so far as was found in the present tests, are more readily oxidised by xanthine- and aldehyde oxidase preparations, than d-trans-7-aldehyde-π-apocamphor (vitacamphor). 2) Decreased. dehydrogenase activities induced by aldehydes returned to the normal level by the addition of cysteine, glutathione and ascorbic acid. 3) Vitacamphor underwent equimolar combination with cysteine, forming an aldehyde-thiol compound. It also combined to a certain extent with glutathione, but not with ascorbic acid. 4) Vitacamphor and other aldehyde appeared to catalyze the non-enzymic oxidation of cysteine. 5) Ascorbic acid with the dehydrogenase systems seems to participate to some extent in the reduction of vitacamphor.
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