Abstract
The relationship between the menbraneous exiability and metabolic activity of frog skeletal muscle was observed. Respiration was increased by a depolarzation and caffeine application below the thresold for producing a contracture, but it was not increased by catecholamine. Ouabain suppressed extro oxygen consumption at low values of depolarization. At higer values of depolarization and caffeine apprication was not suppressed by ouabain. It is proposed that the extra oxygen consumption by potassium depolarization or an application caffeine and anaccompanied by mechanical changes is related to the release of Ca from its bound form.