Folia Pharmacologica Japonica
Online ISSN : 1347-8397
Print ISSN : 0015-5691
ISSN-L : 0015-5691
The influence of DL-Methionine and Thioctic acid on the experimentally injured liver by DL-Ethionine
Kohji SAKAMOTOYoshiko MATSUSHIMATakako KASAHARA
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1972 Volume 68 Issue 3 Pages 330-344

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Abstract
The influence of DL-Methionine and Thioctic acid on the experimentally injured liver in rabbits, were investigated.
The injury was produced by subcutaneous injection of DL-Ethionine in daily dosage of 100mg/kg for three days.
DL-Methionine and Thioctic acid were injected subcutaneously for six days before liver injury.
Liver function tests, such as serum GOT, GPT, liver supernated GOT, GPT, and serum cholesterol were examined.
Electronmicroscopical examination of the liver, were also performed.
The observed findings were that DL-Methionine and Thioctic acid appeared to inhibit the liver injury to a certain degree, and that Thioctic acid appeared to be more effective than DL-Methionine.
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© The Japanese PharmacologicalSociety
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