Folia Pharmacologica Japonica
Online ISSN : 1347-8397
Print ISSN : 0015-5691
ISSN-L : 0015-5691
The introduction of mass psychology to animals in pharmacology-9
Circadian rhythm and mutual relation of El-mice-convulsion at 6:00p.m. to anticonvulsants
Tomitaro KITATaeko HATATazuko OKAGE
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1973 Volume 69 Issue 1 Pages 153-161

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Abstract
It was reported in our 4th paper that there was a biorhythm witn one cycle of 4_??_5 months in inducing El-mice-convulsion.
The biorhythm in El-mice born for 3 consecutive days was quite similar to the rhythm in the group without age-limitation.
Additionally, El-mice-convulsions had a circadian rhythm with 2 peaks in TSC (thre-shold of shaking-number for convulsions) at 10a.m. and 10p.m., with one of the lowest TSC peak at 2a.m. and the 2nd lowest level of TSC peak at 6p.m.
At 6p.m., influence of central-acting drugs as related to El-mice in convulsions was hardly observed, though it was observed at 10a.m.
There was a biorhythmic change in numbers of eosinophile of mice, and the cycle was 35_??_42 days in dd-mice and 42_??_49 days in El-mice.
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© The Japanese PharmacologicalSociety
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