Abstract
As part of a series, a study concerning the mechanism of the antiparasitic action of 4-iodothymol (IT) on Ascaris body and distribution in the various tissues after absorption was made. It was found to be taken up through the mouth and skin, however the percentage through the skin was greater. In 5hr, 50% was taken up at the concentration of 200μg/ml and almost all was unchanged in Ascaris. The rate of 131I-IT uptake was greatest in the head, with muscles of the central body being next. A rather small amount was distributed in the perienteric fluid, the gastro-intestinal ducts and the genital organs.
