Abstract
Norepinephrine (NE) content in the brain slightly but significantly increased when γ-oryzanol (100 mg/kg, s.c.) was given once daily for 1, 5 or 10 days, while NE in the gastric area was not affected. The turnover rate of brain NE tended to decrease with the administration of γ-oryzanol. From the results, it is likely that successive doses of γ-oryzanol increase brain NE by inhibiting degradation or release of NE.
