Effect of HPS on leucocytozoon and coccidial infection in chickens

Abstract

The effect of HPS (halofuginonepolystyrene sulfonate), a derivative of halofuginone with lower toxicity, on natural leucocytozoon and coccidial infection in broiler chickens was evaluated in a floor pen trial. The experiment was conducted from one day to 10 weeks of age. On leucocytozoon infection, HPS added to the diet was completely effective at 60ppm, fairly effective at 40ppm and ineffective at 20ppm. On the other hand, HPS concentrations of 20ppm, 40ppm and 60ppm were completely effective on coccidial infection. HPS at 40ppm which corresponds to the recommended level of halofuginone (3ppm) and at 60ppm had no adverse effect on the weight gain in experimental birds.