Journal of Temporomandibular Joint
Online ISSN : 1884-4308
Print ISSN : 0915-3004
ISSN-L : 0915-3004
Effects of NMDA application for the neural activity of mesencephalic trigeminal neurons
Akifumi ENOMOTO, Reiko OKAMOTO, Hitomi SENOO, Morio KUSAYAMA, Suguru HAMADA, Mikihiko KOGO
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Keywords: mastication, trigeminal, NMDA, rhythmical activity, sodium current
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2009 Volume 21 Issue 2 Pages 99-104

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Abstract
The electrophysiological properties of mesencephalic trigeminal (Mes V) neurons in NMDA-induced trigeminal activity are still unknown. In this study we show how NMDA application affects Mes V neural activity. Additionally, we investigated the properties of subthreshold sodium currents (persistent and resurgent sodium currents) under NMDA application. NMDA application blocked rhythmical burst discharge and reduced the flow of subthreshold sodium currents in Mes V neurons.
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© 2009 Japanese Society for Temporomandibular Joint
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